Reed B. Wickner (c. 1942- ) is an American yeast geneticist. In 1994 he proposed that the [PSI+] and [URE3][1] phenotypes in Saccharomyces cerevisiae, a form of budding yeast, were caused by prion forms of native proteins. Specifically, the sup35p protein.
Reed Wickner graduated from Cornell University with a B.A. degree in 1962. He then went to medical school at Georgetown University and received his M.D. degree in 1966. He is currently (as of 2010) Chief of the Laboratory of Biochemistry and Genetics at the National Institute of Diabetes & Digestive & Kidney Diseases, part of the National Institutes of Health. His research interests pertain to prions and amyloid diseases.